How Does Co-codamol Work?

By: Annabelle Clarke
May 11, 2021

There are many benefits to having two pharmaceuticals in one convenient form. With a combination painkiller, patients do not have to take multiple doses during the day. This is perfect for those who are currently taking strong medication or cannot tolerate various medications at once. The use of combination therapies, such as co-codamol (codeine and paracetamol), can reduce cost and have reported to having greater compliance than when taken separately. However, the most prominent benefit is their corresponding mechanisms of action.

Co-codamol works by the following pathways:

  • Paracetamol- This pain reliever acts peripherally by blocking the impulse at the receptors that evoke pain. Although experts are not completely sure how the medication works, it seems to inhibit the chemical, prostaglandin which is responsible for the feeling of pain. Paracetamol also affects body temperature, which is effective in reducing fever.
  • Codeine- This pain reliever acts in the central nervous system. The medication exerts its effect through mu-opioid receptors, although it has low binding power to these receptors. This attachment brings about pain relief in the patient. The combination with paracetamol has shown high success rates in treating acute pains.

In certain conditions, codeine and paracetamol taken alone do not provide enough analgesia. When it is used separately, it can also elevate the occurrence of side effects of both medications. However, the fixed-dose of both medications in this treatment decreases the intensity and appearance of co-codamol side effects.

How Long Does It Take for Co-codamol to Work?

Co-codamol tablets work by two agents that have the same onset time of action. After taking this medication, patients should expect to feel its effects in about an hour. The method that the medication is taken in also affects the rate at which the active ingredients travel in the bloodstream. Usually, these tablets are coated in a special film, which protects the tablet from stomach acids and other chemicals in the digestive tract. In this way, it may take slightly longer for the therapeutics to reach the bloodstream.

However, co-codamol 30/500 mg tablets are readily absorbed from the gastrointestinal tract and are spread to the different tissues throughout the body before reaching the brain. Combining treatments may affect the patient’s timing and advice on its use, which may also affect its onset time.

To ensure that patients receive analgesia in the stipulated time, they should:

  • Take the medication at the same time every day.
  • Do not crush or dissolve the tablet.
  • Always stick to the dose given by the prescriber/pharmacist.
  • Do not take the medication twice in 2 hours.
Codeine Tablets

How Long Does Co-codamol Last?

All patients that are suffering from pain desire a medication that produces long-lasting pain relief. Single agents are not able to provide such durations as a result of quick metabolization and other factors. Although the duration of effects depends on the co-codamol dosage stated and other factors, combination medications usually last longer than individual agents.

This quick-acting medication can also ease breakthrough pain, which is sudden flare-ups from various conditions. It is beneficial in patients who experience numerous flare-ups in the day. With this medication, they do not have to wait out the sudden bouts of pain. However, it is important for patients to take the tablet as soon as pain is felt to maintain its effectiveness.

Co-codamol takes around one hour to take effect and lasts for three to four hours, depending on the dose. While receiving pain relief, first-time users may also feel tired or lethargic, as the codeine in the medication promotes drowsiness. Following any injury or intense pain, the body requires time to recover properly. One of the most important details of healing apart from painkillers is rest. This medication can provide an adequate amount of sleep to patients by causing drowsiness. Patients should not perform heavy physical activity as it can prolong the healing process.

How Often Can You Take Co-codamol?

Pain medications that are used on prescription or over-the-counter for the management of pain should not be used for more than a couple of days in a row. The specified maximum daily amount should not be exceeded as it may boost side effects. Co-codamol should follow the same routine, as it may increase side effects – in rare cases – can lead to medical complications. This medication should be taken as per the strict prescribing instructions given by the doctor or pharmacist.

This medication should not be used for more than a week. If the pain has not improved or subsided completely, patients should talk to their doctor for further advice. It is usually not recommended to take codeine-containing treatments on a long-term basis as it could lead to dependence. However, this does not occur when patients follow their dosage guidelines. If patients find that they have taken extra co-codamol tablets by accident on a single occasion, it is unlikely to cause negative effects. They should wait at least twenty-four hours before their next dose.

Codeine Tablets Online

Co-codamol Effects

Co-codamol tablets have an impressive safety profile that allows them to be taken with aspirin and ibuprofen if patients require a higher and longer pain relief. These combinations will not cause any severe side effects. This medication produces two types of effects in the body, which is why it is one of the most purchased treatments on the market today. These two effects target the pain and any symptoms it might evoke in the patient.

Co-codamol online reviews show that fever is one of the most common symptoms that accompanies pain. While some pain relievers cannot rectify this symptom, this medication has paracetamol present, which can combat fever associated with pain. Codeine has opioid actions, which have been used for many years for relieving pain. The medication is broken down into its metabolites, with a small part converted to morphine. This provides patients with high levels of pain relief without the risk of taking morphine.

Therefore, this medication provides pain relief paired with symptomatic relief. Additionally, with a fixed-dose combination such as this one, patients do not have to dose each tablet independently. When patients use this medication, they should remember not to take others that contain paracetamol.

Our platform offers responsive customer support and product information to ensure patients are assisted and informed when they buy co-codamol online.

More Helpful Information About this Product

  • What is Co-codamol?
  • Co-codamol Dosage Guide
  • Co-codamol Side Effects

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